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Exosome-associated tau is secreted in tauopathy models and is selectively phosphorylated in cerebrospinal fluid in early Alzheimer disease

Simultaneously, growth hormone and IGF-1 modulate osteoclast activity to promote balanced bone remodeling that maintains skeletal integrity while allowing for adaptation to mechanical stress and repair of microdamage

In atherosclerotic blood vessels, cholesterol crystals stimulate an immune cell inflammasome called NLRP3 that then triggers a cascade of inflammatory and thrombotic signaling

And the actual hyperreactivity of the HPA would be missed

My hairdresser noticed before I even said anything at my next appointment